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Home Journal of the American Heart Association Vol. 6, No. 4 Benefits of Permanent His Bundle Pacing Combined With Atrioventricular Node Ablation in Atrial Fibrillation Patients With Heart Failure With Both Preserved and Reduced Left Ventricular Ejection Fraction
become a more attractive alternative to BiV pacing for CRT with the demonstration of resynchronizing ventricular activation by various groups[14]-[18]. The physiologic benefit of permanent His bundle pacing (HBP) is the ability to stimulate the ventricles through the intrinsic His-purkinje system, which results in synchronous and a In a further embodiment, the His bundle pacing is delivered subsequent to the biological therapy to enhance the biological therapy. Additionally, the His bundle pacing maintains or improves hemodynamic performance of the heart, such as increasing stroke volume and ventricular synchrony, at least until the biological therapy is successful.